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财神争霸:王泉德

点击数:4113 来源:财神争霸 作者: 录入:财神争霸 更新时间:2019-11-12

财神争霸:

财神争霸:联系方式

       电子邮箱:quande_wang@163.com

       办公地址:国家重点实验室2号楼503


研究方向

    1. 自由基氟化学

    2. 含氟功能分子药物化学研究


教育背景

       2015.08 至 2019.11,香港中文大学化学系,博士,导师:Gavin Chit Tsui

       2009.09 至 2012.07,山东大学药财神争霸,硕士,导师:方浩教授

       2005.09 至 2009.07, 山西医科大学药财神争霸,本科


工作经历

       2019.12 至今,广西师范大学,财神争霸/省部共建药用资源化学与药物分子工程国家重点实验室

       2015.03 至 2015.07,云南白药集团创新研发中心

       2012.07 至 2014.11,药明康德新药开发有限公司


独立工作后论文发表情况:

1. Shichao Tian, Ning Chen, Keguang Cheng*, Quande Wang*Radical Acylfluoroalkylation of 1,3-Enynes via N-Heterocyclic Carbene/Photoredox Cooperative Catalysis. Org. Lett. 2024, 26, https://doi.org/10.1021/acs.orglett.4c01372.

2. Mingxi Chen, Quande Wang*Fluoroalkoxylating Reagents in Organic Synthesis: Recent Advances.  Eur. J. Org. Chem. 2024https://doi.org/10.1002/ejoc.202400316 (Invited review).

3. Feng Liang, Ning Chen, Keguang Cheng,* and Quande Wang*N-Heterocyclic Carbene and Manganese Synergistic Catalysis: A Three-Component Radical Acylmonofluoroalkylation of AlkenesOrg. Lett. 2023, 25, 8168?8172. 

4. Shichao Tian, Mingxi Chen, Yihan Tang, Keguang Cheng*, Gavin Chit Tsui*, Quande Wang*. Acylmonofluoromethylation of alkenes via dual NHC/photoredox catalysis. Org. Chem. Front. 202310, 6124-6130. 

5. Yuqing Zhou, Shichao Tian, Lixin Shen, Liqiong Zhang, Jingjing Liu, Weibin Mo*, Quande Wang*, Keguang Cheng*. Design, synthesis and in vitro antitumor activity of 17β-estradiol-amino acid derivatives. Arab. J. Chem. 2024, 17, 105539.

6. Liqiong Zhang, Li Sun, Yuqing Zhou, Jingjing Liu, Quande Wang*, Weibin Mo*, Keguang Cheng*. Pentacyclic triterpene-amino acid derivatives induced apoptosis and autophagy in tumor cells, affected the JNK and PI3K/AKT/mTOR pathway. Bioorg. Med. Chem. 202394, 117478. 

7. Shaoting Chen, Yuxiang Zheng, Benji Liang, Yudong Yin, Jian Yao, Quande Wang*, Yanghan Liu*, Nouri Neamati*. The application of PROTAC in HDAC. Eur. J. Med. Chem. 2023260, 115746. 

8. Yudong Yin, Li Sun, Lixin Sheng, Liqiong Zhang, Jingjing Liu, Xiaoan Wen, Weibin Mo, Quande Wang*, Keguang Cheng*. (4-Picolylamino)-17β-Estradiol derivative and analogues induce apoptosis with death receptor trail R2/DR5 in MCF-7. Chem-Bio. Interact. 2023369, 110286.

9. Kun She, Feng Liang, Shichao Tian, Hengshan Wang*, Gavin Chit Tsui*, Quande Wang*. Organocatalytic Three-Component Acyldifluoromethylation of Vinylarenes via N-Heterocyclic Carbene-Catalyzed Radical Relay. Org. Lett. 202224, 4840?4844. 





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